Do you have multiplayer on or off?
So, further possible finding. With multiplayer off, I was able to do a flight of 88 minutes from ramp to ramp without crashing, so it seems that the one hour “limit” I was experiencing may only apply with multiplayer active.
May I clarify, do you mean flying without multiplayer on, without the crash?
Typo, sorry, I meant with multiplayer off.
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i will try the same and see what happens. Thx mate.
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Been up flying since then, seem wroking great without he multiplayer on. 
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Yes multiplayer is on. However I have finally completed the long haul flight. No CTD. All I did was detach the VFR Map from the sim and lowered the Cockpit setting to medium. I will try again in the morning with a domestic flight
Good luck, for both of us 
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After the latest version 1.9.3.0, I have CTDs even in menus.
If I leave the sim about hour or two in menu, when I return the sim has CTDed.
-eelis-
The same happend to me too… Usually around 1 hour into a flight, it CTD.
I have tried turn off Text-to-speech, not to use AI ATC, have the VFR map shown as soon as a flight starts, but no luck.
I am now flying with the multipalyer option turned off at the moment, the flight have been up since almost 2.5 hours ago… everything seems working ok.
I am brocasting my “experimental” flight at twitch, feel free to share my moments. Twitch
This fixed it for me too. I wonder if it’s a model loading/existing issue? I don’t have the deluxe version, so I wonder if people who do are crashing me. Haha. I’m going to try turning on generic modes for multiplayer.
Cool, may be I will try it too. 
That is actually a teething problem that has existed since launch.
There’s no vsync in the menus and they unnecessarily play a 3D scene behind the menus that isn’t as heavy as the rest of the sim. This will cause most video cards to go completely overdrive straight to 100% utilization and crash the sim.
Luckily, a workaround exists. From the software of your own video card (NVIDIA control panel if you have a Geforce) you can force limit FPS to 60 for Microsoft Flight Simulator, and it’ll prevent this issue. I haven’t had a crash on menus since.
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I just finished a full 4 hours flight without any problem. Thx for the advice
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Yes it was the A320. Flightime was something just over an hour. I actually opened the Flightsim yesterday and stayed in the main menu and set a timer…exactly on the 60min mark the game went back to desktop.
Absolut weird
Try turning off multiplayer completely. It has worked for me to stop the CTDs completely and it seems to be working for others as well.
I will be doing a flight now with multiplayer off and report back afterwards. Thanks
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So you seem to be on to something there…I had Multiplayer disabled and it took me 1h 20min Gate to Gate and the Game did not Crash. I am a happy Simmer right now. CTD´s somehow got to do with Multiplayer as it seems
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Hi - Just to confirm, is this what I want? Does having Live Air Traffic on matter? Do you know if there’s a way to shut Multiplayer off by default? I’m about to try the same flight I tried yesterday where it kept crashing. Will report back once I an answer.
Edited to add screenshot of MP screen.
I know they have broken the VFR map, something that worked just fine up until now. Asobo should never have been given this project, they have failed.