I don´t have iCUE and still have very frequent, periodic and very long freezes. They started with AAU2 and just went worse with SU14. The problem is on the game main thread not elsewhere. It just hangs and you can see how CPU usage drops close to no utilization during the freezes. If the problem was elsewhere you would not see such CPU drops, as processor would still need to work to maintain the required workload for a normal MSFS gameplay.
Cheers