Airport to airport

You have a few options to achieve this.

  1. Just enter the new flight plans in manually, call the fuel truck (or just use the weight and balance option on the toolbar) to adjust fuel / cargo / passengers / etc…

  2. If the aircraft you fly supports it, import your flight plan from the supported source

  3. Ditch the in-sim ATC and use something like Pilot2ATC, VATSIM, etc… that does not require the world map.