Just to also add, if, like me, you like to have a batch file to start everything up for flight sim…
Take that script, put it into note pad and save it as a .ps1 file, e.g. I’ve called mine fixusb.ps1
Then add the following to your batch file:-
PowerShell -NoProfile -ExecutionPolicy Bypass -Command “& ‘C:\fixusb.ps1’”
As long as you run your batch file as admin, seems to also run the shell as admin so you don’t have to click the admin popup twice… this should then set most usb devices to untick that box before you play the game 
This is now my startup script just as an example:-
@echo off
PowerShell -NoProfile -ExecutionPolicy Bypass -Command “& ‘C:\fixusb.ps1’”
cd "C:\Program Files\SPAD.neXt"
start SPAD.neXt.exe
cd “C:\Program Files\Air Manager”
start Bootloader.exe
cd “C:\Program Files\LittleNavmap-win64-2.8.8\LittleNavmap-win64-2.8.8”
start littlenavmap.exe
cd “C:\Program Files (x86)\msfs-popout-panel-manager”
start MSFSPopoutPanelManager.exe
cd “C:\Program Files (x86)\Steam”
start steam.exe steam://rungameid/1250410
exit
This opens my flight sim programs and then starts the sim