Back at the turn of the year when the whole CTD thing blew up I found the way around it back then was to turn off AI traffic and it worked 100% of the time. I can fly with live weather with no issues either. The other day while running a route for OnAir in my C172 (previously the most stable of platforms for me) I got a CTD when I had live weather AND live traffic. Turned it all off and everything was fine.
Don’t get me wrong, when I’m coming in to land the sim will still sometimes hang for 3-4 seconds then stutter a bit before continuing in any plane and in any situation but it avoids the total CTD. And I’m running 32Gb of RAM an SSD and a reasonable internet connection.
In a nutshell, my advice is run with no traffic and no weather for pretty much 100% no issues. Turn on live weather maybe brings it down to 99% reliability. Turn on any sort of traffic (live or AI) and its a lottery, sometimes you’ll get a way with it but mostly not.