I’ve had it happen to me on occasion. I figured I must’ve either hit an additional # key on my keyboard or inadvertently hit both # 1’s and 2 at the same time when responding. I usually use the keyboard #1 as that is usually the correct response to any (most) calls from ATC. I don’t usually have the ATC dialogue window open unless I know there will be additional instructions coming down such as on an approach or after touchdown.
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