No reason it can’t help especially if its closing things that are using resources I sometimes use the Razor cortex game booster which cleans unnecessary things from the ram sets the power mode for best performance, though turn that part off cos already set in windows and NVidia control panel.
Personally I can’t say I notice much of a difference but that may depend on the hardware or how people’s pc is setup.
I recently found out when getting more ram that using a Ram cache to use spare ram up works well to reduce stutters and gave me a nice fps boost 3 to 5fps which for me can see in the dev mode fps viewer that it has helped with the mainthread. was able to turn both object and terrain detail slider up from 100 to 200 and see equivalent or better performance now.