Check to insure you do not have ailerons linked to control rudder under the “Assistance” settings. (This would normally be used only when your flight sim setup does not include separate rudder pedals).
When taking off in a crosswind, you need to hold aileron into the direction the wind is coming from. I.e. right aileron with a right crosswind. Rudder inputs alone are not sufficient to maintain the runway centerline with a crosswind.