Don’t skip on the ground at unfamiliar small airports. The blue parking squares are sometimes on top of buildings and you will crash if you skip to parking. Write these down because spawning into these airports also crashes you instantly upon spawning in.
Always get the lowest insurance as it pays out 0% at every tier.
Get out of small GA aircraft as soon as possible. The turbulence model in career is cranked up to 11 and you will find it nearly impossible to land at some airports.
ATC will vector you into the side of a mountain. Be aware of your flight plan and the maximum altitude you need and ignore ATC if you have to.