In my experience, this CTD often/only happend, when my CPU and GPU were overclocked too much. After WU3 I experienced a higher “critical OC-behaviour” of the sim than before the update. Maybe it´s due to the currently reported CPU utilization after the Update.
On some flights it happend, on some flights not. But hence I´ve dropped my OC CPU in Mhz and also my GPU, everything is stable. May this is a option for you?