I think MSFS is very sensitive to any overclock. I was getting crashes when I had an overclock on my 3070. I will say I had no stability issues on any other game that frankly pushes the GPU much harder. I’m CPU pegged most of the time so my GPU is rarely “pushed” on MSFS.
The CTD’s stopped completely when I removed the overclock. I now have a profile set in Afterburner purely for MSFS.