Hi,
What kind of throttle do you use?
I have the Honeycomb Bravo and the setup is simple.
You must not have a profile in the MSFS configuration.
In the CRJ, you go to the tablet, Options, Throttle Calibration.
If you have a Honeycomb or similar, you place the following items:
Throttle Type: Dual Axis
Reverse Axis: Disabled
Then you place your throttles on IDLE position, then you go to the tablet and you click on SET at IDLE.
You place your throttles on CLIMB and you click on SET on the same position, CLIMB.
You do the same for TOGA and MAX POWER.
For your reverse, you will need to create your key with the MSFS options.
You can watch this video : Aerosoft - HowTo : Honeycomb Bravo & Aerosoft CRJ Detents Calibration - YouTube
If you have other hardware, the logic is the same.