CTD after spiking to 100% GPU

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I’ve had issues with MSFS crashing since SU5. I’ve had multiple instances of CTDs, and each time that I can remember it had a 100% GPU spike before the crash, with both of my displays freezing. I’ve tried just about everything imaginable under the sun (excluding an OS wipe), with no luck. It seems to vary from 10 seconds to 30 minutes after loading into a flight that the sim crashes. I also have my Rift S plugged into my computer, although I do not use it for flying in MSFS. Any help will be greatly appreciated.

My specs:
GPU: RTX 2080 Super (not OC’d)
CPU: Intel i9-9900KF (not OC’d)
RAM: 32GB @ 3200MHz
PSU: Corsair RM750, 80+ Gold
Drives: 128GB Samsung 2.5" SSD - OS (yes I have enough space)
2 TB Seagate Portable Drive
1 TB Samsung M.2
1 TB WD Blue 2.5" SSD

All components except for some of the drives are about 3 years old.