Do I have to set-up a profile in Controls Options for each aircraft type that I fly?

Thanks Neo. Guess I’ll have to do as you suggest. I spoke too soon when I said my FBW A32NX worked well. I’m still having problems with that aircraft’s throttle. I’ve been using Microsoft Flight Simulator software since 1995 and I do not recall having trouble connecting my old CH Products Yoke LE in the numerous previous editions of the simulator. There were no regularly scheduled updates bringing changes to the sim environment in the old days and I think I’ll have to start studying how to properly configure a proper profile for each type of aircraft I wish to fly. This means I’ll probably be flying a lot fewer aircraft types than I used to, given the work involved in the creation of each profile and the additional step of having to open Controls Options at every change of aircraft.