Hello and thank you for your reply.
I did not change the ESC key assignement and try to default reset all the keyboard/mouse/joy and so on. For information, I use an AZERTY keyboard.
This situation seems to happen randomly. Most of the time there is no problem but when it happens and you want to save a flight…
Another thing that could help to solve is that most of the time I have A BSOD each time I launch FS2020 then reboot one or two times and after it is ok. I think it happens each time there is an upgrade.
I try to reinstall everything (WIN10 + Drivers + FS2020) but same thing. I never had these problems on other sofrtware or games.