For all controls with more than two positions - i.e. three position switches or rotary knobs - the mouse wheel can be used to change them. It works very well in terms of tactile feedback, since the action is similar to flicking a switch.
For the sake of consistency, the same should be true with two-position switches, but the mouse wheel does nothing.
For example the A320’s exterior lights panel has a mix of two and three position switches. The three position switches can be controlled with the wheel, but to change a two position switch you have to click it.
This probably doesn’t sound like a big deal but I find it really breaks immersion.