ESC causes flight system failure

During flight with the A320v2 when I pause the flight with ESC on the keyboard it causes the flight to have severe electrical issues or hydraulic problems.

I have had no replies to my post re using esc and pause. The issue is still occurring, but only with the Neo Version 2. The original version there are no failures after I return to the sim. With V2 I cant even take a toilet break with the flight unraveling. I cant believe that I am the only one having this issue. Hope someone can give me some feedback. Thanks.
BW