Search Engine is your friend. We have many, many, many threads on CTD.
You’ll need to dig deeper - things like check your WIndows Application Event Log to see if there’s a useful Stop X error message in there.
Remove Mods and any Third-Party utilities using FSUIPC/SimConnect
Are you overclocking GPU / CPU?
Tons of things to try, but the first step…is to Search. 
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