Only once or twice, usually on the ground after landing where the AI can’t tell whether I want to taxi to the gate or to take off. And when we’re suppose to get clearance for take off, because it doesn’t seem to register that I’m in position.
I never need to restart the sim. I just open the ATC window and make a response, and the AI comms usually take over again afterwards.
AI comms issue never happens to me when cruising for frequency change handover. Only happens on those two examples I mentioned.