For me this setting is the only one (since 2020) that enables some cockpit view axes in VR. Without this on the cockpit view in VR can be turned only by own physical head. With this setting on you can use yaw and pitch view axes (no the lockable ones!) assigned to a joystick’s mini stick etc. If you assign those axes to a mouse then you lose totally the ability to click on buttons.
Also same setting (“home cockpit mode”) makes copilot view switchable only via toolbar. once you use the toolbar then you can switch the position with Next and previous cockpit positions buttons but not with the dedicated switch to copilot view one! that one works only in 2D.