How do I remove peripheral drivers from MSFS?

Unplug the winring and check if this is still the issue ( greyed out ) with other things, like keyboard mouse. Maybe plug the Thrustmaster back in and check it too.

But it may be something specific to the Winring Orion.
I did a quick search in this forum but couldn’t find anything on this joystick, but there may be others using it here.

Maybe change your header to say Need help with a Winwing joystick setup.

Do they have a support site or user manuals?
I found these:
wwsimstore & this faq
It may need special install or windows install to work correctly.

You may need to seek help and search outside of msfs.