After the Patch I did start with having 6 CTD in a row. 4 Yesterday and 2 today.
I did again flash the DNS, cleaned the rolling cache inside MSFS and cleaned the shader cache inside the NVIDIA Driver.
After all of this I was able to start 3 flights in a row. I am slightly optimistic and looking forward to experienceing the Sim as a lot of others do.
This said, if I can continuesly start a flight without CTD I appreciate what MS did so far!