VFR very rarely, I usually do trim for hands free operation though. AP if for some reason the plane will not settle and I’m on a long cruisey flight or I need to briefly step away. Many of the planes I fly don’t have AP, and if they do I’ve never used it.
Airliners I mostly hand fly the departure, put AP on during climb and cruise, then leave it on for most of the approach, I always hand fly the arrival and landing. I always run the checklists and pilot workload for me is very high coming into the arrival so I don’t have time to hand fly it.