I have long been a VR user since the early Oculus Developer Kit - 1 was released.
I have over the time ended up owning a few HMD including Oculus DK-1, DK-2, Rift 1, and pre-ordered the G2.
Over the years my biggest shortcoming with VR are 2 folds.
1 - Getting into VR involves preparing. If you were glasses like I do it can get uncomfortable depending on the shape of the HMD and often I end up switching to contact lenses for the comfort factor.
Also if you don’t live in a spacious house, it requires having enough room around you to swing your arms and not hit objects around you.
2 - Since VR games are super immersive it also ends up draining a lot more energy compared to just playing on a monitor. This now is very specific to the VR experience your consuming. So a lot of FPS genres end up being so demanding that after a few hours of playing you do get exhausted. For a flight sim however I don’t think this would be the case.
So yes in a nutshell the preparation involved in playing comfortably (for a lot of people), the amount of exhaustion you experience in VR games are the 2 short comings I see.