First of all, I’m not a helicopter expert 
, I only did the basic tutorials (very useful anyway) and a lot of practice (even extreme to understand how the aircraft reacts) to best dose the controls. I use the collective on the A and B buttons of the controller and it’s exhausting to keep pressing up and down to keep a balance. For the settings I only use the tail rotor assistance (no on the collective and no on the cyclic) and the assistance on the controller sensitivity. In the controls (which are the default ones) at the moment I have raised the sensitivity of the cyclic axis to 0.75 because I feel like I have a more precise response to the micro movements of the Stick. For the H125 I add that up to 80/90 knots it is quite manageable while at higher speeds it becomes a crazy horse 
I found this video helpful for general basics :
