Compared to Seneca the P-38 is very agile. Compared to a Hurricane or A6M Zero … not so much 
As has been said before neither the Seminole nor the Seneca are especially agile aircraft. Especially the Seneca was built for traveling in comfort so it’s very stable. The Seminole is a little more sporty and maneouverable than the Seneca. But the single engine aircraft like the Mooney and especially the Waco are far more agile than those two Twins.
In general from all the Carenado planes currently on sale, the Mooney is probably the best compromise between fast (in a straight line) and maneouverable.