Occasionally. I didn’t notice VR made much of a difference.
Other than the tablet which didn’t always work. I’ve read if you go in and out of the menu it can jack up the mouse as well.
Honestly it sounds like you have something bound to the switch that you need to track down. I have flown the 208 n VR tons of times and never had any problems.
The game has default bindings on peripherals for many of the starter/electronics related items and probably this is what is biting you.