When you folks say “lock-up” do you mean that the screen is totally frozen? I have an RTX 2080 Super and what’s happening with me is that my FPS goes from 30’s to 2-3. I can see that the sim is still running, altimeter is changing, scenery is moving etc, but not useable and only way out is Ctrl-Alt-Del.
I too will be trying DDU. I’ve rolled back to a few different versions of the Nvidia driver, as far back as Feb '22 with no luck so I am worried that maybe they really aren’t clean installs.