I’ve had mine “lock up” while being used… but I attribute that to spinning the dial too fast and things get confused. Sometimes after a minute or two it’s back online, but other times I have to exit and reboot my PC. Likely a USB concern in my case.
Jim-Sim
[Edit: No funky software in my case (SPAD, FSUIPC, or anything like that), just the Logitech driver.]