Mouse stopped working

After doing update, msfs, my mouse does not work when it comes to interacting with anything in cockpit. I am able to move around cockpit, and interact with atc but thats it. I have also upgraded graphics card, but dont know if that would have anything to do with this issue. Any help would be greatly appreciated as not able to do anything. Have looked on youtube and tried the possible fixes they referred to. Thanks.

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Check in options that the update hasnt switched you from “full screen” to “windowed”. Sometimes affects mouse operation.

Thank You very much, am going to restart everything and give it a shot. Have been pulling out hair, did not have much in first place, trying things.