Thx @MSFSRonS , well done. While I haven’t tested it, I believe not saving bindings is related to where you stated:
"Be careful of which the Presets are displayed when executing the “Save and Back”.
I believe the sim will only save those exact 3 profiles. In addition, I suspect if you flip to another profile and then back you’ll lose any new bindings you made to the profile you moved away from before pressing save and exit.
The fact that no pop up is displayed warning you that you will lose any changes just shows how quickly this interface was put together and not tested.