MSFS2020 "Kills" TWCS throttle. Makes it unresponsive even after quitting sim and affects other titles

Do you have any add-ons in your Community folder? If yes, please remove and retest before posting.
Yes, but removed when testing, issue present regardless.

Are you using Developer Mode or made changes in it?

Brief description of the issue:
MSFS Makes TWCS throttle “sleep” and does not detect inputs even outside of the sim (windows Calibration or other calibration subject) Issue is only present the first time MSFS is run and gets solved by unplugging the throttle and plugging it back in and restarting the sim.

Issue does not happen with any other titles, however if the throttle is affected by MSFS it will also not work in other titles at least until I unplug and plug back in.

Provide Screenshot(s)/video(s) of the issue encountered:
Not available at this time.

Detail steps to reproduce the issue encountered:
Start a flight and try to increase throttle or use any inputs in the throttle, it is not limited to axis.

PC specs for those who want to assist (if not entered in your profile)
Info in profile.

Did you submit this to Zendesk? If so, what is your ticket #?

I’ve just experienced this too. I restarted msfs 2020 but no good. Restarting windows 11 got it working again. I wondered if it was windows or the thrustmaster driver. Did you resolve it after and did it happen again?