I can’t help you much with this because it is highly hardware and software dependent, that is what exactly is on your own system.
In general with similar hardware and software you’d expect similar (or close) outcome. What you describe looks more like an outlier performance and this begs the question indeed.
Win10 is smarter than previous Windows in terms of process, resources and scheduling. Drivers are complex too but they operate within known hardware characteristics/limitations and known APIs. With this knowledge you’re better prepared to understanding what it is each driver setting is mostly doing.
Also, some settings could be misleading like Multithreaded Optimization. In your opinion what would you expect this setting to do?
For in-depth understanding of the current problems and solutions about multithreading and GPU I’d recommend this article:
Understanding DirectX Multithreaded Rendering Performance by Experiments
And this one published a year before (mostly explaining the same with some variations):
Performance, Methods, and Practices of DirectX* 11 Multithreaded Rendering
Even if you’re not digesting all of the article, reading the first chapter (introduction) will certainly give you a clearer view of what it is your video card is doing in regard to rendering the game visuals
So now back to my question, what it is this “Multithreaded Optimization” is really doing?
I’ll give you my own understanding which is not what you’ll find in searching online: this has nothing to do in leveraging multi-core or HT for the video card driver so that you get additional performance. This has to do in providing a safety net for older games which were not coded for multi-threading properly. In general you better leave this setting off for better performance with modern games, and on for older games.
Having said all this and back to your question, I’d tend to say:
- first and foremost don’t try outsmarting your system. This means in particular: don’t change process priority at all, leave it normal to get started.
- Then you might want to review the Freesync settings and see what about disabling Freesync (if there is any such setting on the monitor itself) or at the NVidia CPL level otherwise
- Then disable game VSync, because my settings are recommending using NVidia CPL Vertical Sync FAST which is probably not best with Freesync.
These are just starting points worth comparing with.