I get this also when I plug in my Flightstick after FS2020 installs.
I click customize.
It uses my regular profile.
Which is the profile displayed on the Controls Options screen.
If my Flightstick is plugged in before, I dont get it.
Edit:
I should have stated that my controllers are on a USB HUB
with on/off switches.
The above occurs when I forget to turn the switches on the Hub to on.
I normally turn them off when not flying.