That is a heck of a setup there! Certainly above “plug-n-play” I think so I would expect to have to do some serious tuning. My setup has taken me ages to tweak just to get usable FPS, triple screens again, I tried 4K but the 3080ti just could not do it so went down to 1440p instead.
I don’t think anyone goes PC just for ‘easy’, its a trip into the world of options…