First thing to do is disable any startup items in taskmanager, they are not crucial and be careful to keep any addons including ones you run in the background updated. Test both DX11 and 12 to see which performs best. As mentioned a negative voltage curve tweak can work like magic, I now boost to 4850MHz with zero increase in temps compared to stock (I can easily get 5 gig plus but then it gets hot and loud).