Quad views lets you control more finely the resolution, as opposed to VRS which only lets you coarsely select 1/2 - 1/16x reduced resolution. With quad views you can set slight supersampling in the center region to increase quality. To do what with VRS, you’d need to bump the overall resolution up, but then the 1/2 - 1/16x might not help you compensate for the loss of performance without too much of visual degradation.
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