Also depends what and where you fly. I’ve added a screenshot of my settings below. Use this for GA (mostly JF Piper) and occasionally the WT CJ4. Even the DC6 runs okay but usually turn the clouds down to MEDIUM to help. I don’t fly the airliners.
On the game settings, it seems to be the render scaling and the volumetric clouds that are the performance killers. When flying GA, I do sometimes switch up trees to HIGH and grass to MEDIUM … doesn’t actually seem to make much of an impact on performance. I have Game Mode ON and MSFS set for HIGH PERFORMANCE in graphics settings, but not really sure if that made a whole lot of difference. HAGS absolutely definitely OFF.
I did play around with OpenXR settings, but have ended up back with Render scale =100% and reprojection OFF. On the last one, a lot of folks prefer reprojection on; but I found there was too much scenery ‘tearing’ for my liking.
I will typically reboot before starting MSFS and kill everything that I can (I have a recent and pretty ‘clean’ windows installation anyway). Usually have OnAir app running, and sometimes Audible.
One last thing - if you are likely to switch between VR and 2D, I’d suggest turning your MSFS PC graphic settings to LOW … this makes switching between the modes much faster (and I’m pretty sure avoids at least one potential cause of CTD…)
i7 9700 3.6GHz, RTX2080Ti, 64Gb RAM, 471.11 driver, Reverb G2. Typically getting 30-40fps in VR.