Thanks, I found a couple more articles and the page on AMD’s web site with some sample bits about “Radeon Image Sharpening”: https://www.amd.com/en/technologies/radeon-software-image-sharpening 
From what I’m reading, I think it may make things look a little nicer outside the window, but it’s unlikely to improve clarity of text on the glass cockpit displays etc.
It’s a “contrast-adaptive” sharpening filter, which tries to add high-frequency contrast where the image is soft and blurry (thus, enhancing soft details). Instrument gauges and glass displays are already high-contrast and likely won’t get sharpened much, if I’m reading correctly, and if they are I don’t think it’ll add much detail on top of upscaling of text & line graphics.
However, it probably doesn’t hurt either!