Time put MSFS in drawer and load up X-Plane again

My machine ran MSFS2020 great at full ULTRA, once SU5 came out I can’t use it, I get CTD every time.
No issues until SU5 for me. I did a fresh install of W10 and MSFS2020 with same results.
Tried it just watered down an still same results.
I’ll try again after W11 Load.
I have a high end system and I know my PC’s very well, so not sure what is going on, but SU5 is where it started.