Do you have any add-ons in your Community folder? If yes, please remove and retest before posting.
Yes, Mods always worked and fully updated. Using the Flying A320 FlyByWire mod when the sim crashed on me.
Are you using Developer Mode or made changes in it?
Nope, Always disable it when doing major recorded flights. In fact, never enable
Brief description of the issue:
Doing a three hours flight from La Paz (SLLP) to Rio De Janeiro (SBRJ) in the A320 with the FlyBywire mod. No other addons used around the location of the flight. I did this flight two times and twice it crashed (CTD) in flight. Around 40mins into the flight, it crashed to the desktop with no errors and anything.
Weird how did this flight two times and crashed two times near about the same location between (SLLP) and (SBRJ) around 40mins out of La Paz. And so no idea if it’s the sim and or location that makes it crash
Provide Screenshot(s)/video(s) of the issue encountered:
All on twitch 
Clip below:
Hope that this helps, just CTD right away
Detail steps to reproduce the issue encountered:
Run as admin, update everything, fly with no mods installed with default A320
PC specs for those who want to assist (if not entered in your profile)
Motherboard: Asus ROG Strix Z490-E
Processor: Intel Core i7-10700K 5.2GHz
GPU: Asus GTX Strix 1660TI
RAM: Corsair 32GB 3200Mhz Vengeance RGB
Case: Phanteks Pro M Tempered Glass
CPU Cooler: Corsair H115i PRO
SSD: Samsung 850 Evo 500gb
SSD: Crucial MX500 1TB
HDD: WD HDD 2x 1 TB + WD Blue 2 TB
PSU: Corsair RM850x 80 gold
Did you submit this to Zendesk? If so, what is your ticket #?
Nope, I did not.