I also tried the mission again today on the latest 1.30.11 and I see the same results, I get around 8-10 FPS immediately after the loading screen 
How odd. I have all my mods enabled too. The mission was a bit of a let down after all the waiting lol. The pre scripted ATC even bugged out a one point, I was on short final into Naples and the copilot told me we were drifting left and to correct left to track a vor from the beginning of the flight. This was after he acknowledged our clearance and had me put the gear down and full flaps.
Custom flights are the way to go.
Got good news to report! It seems that whatever was causing this bug has been resolved for me in SU15 beta (v1.37.4.0). I’m getting good performance now with manipulators no longer being the top limiter, I’m now back to being main-thread limited which is the expected result with my config.
So, if someone else can confirm my findings I think we can then close this bug as resolved in SU15 
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