The possibility of having different profiles within the VFHub application is currently being studied by the Software Development Team, but it is not a priority at the moment. If you want to use different profiles, MSFS offers the option to create multiple profiles with different sensitivity curves.
If you want this functionality, you will need to disable the devices in the VFHub application and assign all axes/buttons directly within the simulation platform. Once assigned, you will have the ability to adjust sensitivity curves for each profile you create.
I hope this helps!