I upgraded from 32gb to 64gn during the era of the great stutters.
The sim actually seemed more stable and I experienced fewer major stutters.
Some major changes were made to the way the sim handles memory in SU5 so I rarely see it use anywhere near my max physical memory at present.
However, I picked up a tip on these forums and I’m presently experimenting with a 16gb ram drive on which I run the rolling cache and it seems to work quite nicely.