X-Keys in MSFS

Hi all,
I am attempting to use an X-Keys 58 USB keyboard with MSFS. The keyboard outputs keystrokes in MS Word just fine but nothing happens in MSFS. I can have options/controls open on my main screen, MS Word open on a second screen and type on the regular PC keyboard and see the output in MSFS and Word but when I press a key on the X-Keys it only outputs in Word. Is there some kind of binding I need to do to get MSFS to see the X-Keys?