MSFS is very, very sensitive to controller issues.
There are lots of posts in here from users who have had issues only with MSFS.
A controller that acts fine in other sims, can have major problems in MSFS.
I read one thread where the poster, out of sheer desperation, as they had tried everything else, purchased a new controller, even though his current one worked perfect in every other sim/game he had.
Plugged in the new one, problem solved.
I would try a null or empty set profile for the throttle that eliminated the switches as recommended by
MarkManner.