This is interesting, I am on my 6th hour of flying (OIII-OIAW-OIII, OIII-OIMB (on the way) and have not had any CTDs. I also have GSX installed and am running it. I never have the live traffic or multiplayer on but the live weather is on. SU10 beta (5), steam version. (California, USA).
i9-12900KF, RTX 3090, 64GB DDR5 4,400 MHZ…
Regardless, hope the issue is resolved.
And with me CTD, about 20 minutes (VR with G2) then CTD. No Beta SU-10. 
And another…
Faulting application name: FlightSimulator.exe, version: 1.26.5.0, time stamp: 0x00000000
Faulting module name: ntdll.dll, version: 10.0.19041.1806, time stamp: 0x1000a5b9
Exception code: 0xc0000374
Fault offset: 0x00000000000ff609
Faulting process id: 0x4c84
Faulting application start time: 0x01d8b4decf4cc30b
Faulting application path: C:\Program Files\WindowsApps\Microsoft.FlightSimulator_1.26.5.0_x64__8wekyb3d8bbwe\FlightSimulator.exe
Faulting module path: C:\WINDOWS\SYSTEM32\ntdll.dll
Report Id: ed6acf24-0af7-4b4e-a7b8-621ad8b10f13
Faulting package full name: Microsoft.FlightSimulator_1.26.5.0_x64__8wekyb3d8bbwe
Faulting package-relative application ID: App
Fault bucket 1906496581069838172, type 5
Event Name: MoAppCrash
Response: Not available
Cab Id: 0
Problem signature:
P1: Microsoft.FlightSimulator_1.26.5.0_x64__8wekyb3d8bbwe
P2: praid:App
P3: 1.26.5.0
P4: 00000000
P5: StackHash_148b
P6: 10.0.19041.1806
P7: 1000a5b9
P8: c0000374
P9: PCH_C6_FROM_ntdll+0x000000000009DA94
P10:
Same problem…. Never had CTD on MFS but now is all the time. Even after full windows and mfs reinstalled from scratch.
Same problem since 2 days, no GSX, last nvidia drivers, good config, and no problems before this week.
I’m seeking everywhere with no solutions. 
If you’re getting the CTDs that are reported with a “Memory could not be read” message, please, please, please go to MSFS Application Error - memory could not be read - Bug Reports / CTDs - Microsoft Flight Simulator Forums and register your vote.
No it’s : ntdll.dll : C:\Windows\SYSTEM32\ntdll.dll
Then no need for you to bother, but others here are reporting “memory could not be read”
I thought I’d replied to the thread, so sorry if I replied to your post directly.
Just wondering,
Does it make any difference which server is selected?
What about finally creating some application.log so more tech savvy users could maybe figure out where could be root cause and don’t bother devs if problem is on their side. Im regularly getting 0xc0000005 like once per week, tried every possible thing (I do system admin for living, so not typical BFU) and still not figured out the problem.
It would be expremely helpful to have that even if just to check through it and diagnose CTDs one might get at the loading stage to i.e. see if it’s crashing reading a specific addon file or something like that.
Plus certainly it should be helpful when submitting tickets to be able to attach a log file so support/devs can have a better understanding of what the sim was trying to do when it crashed.
100% support a verbose logfile being made available.
1st CTD in a long time. Log says that the culprit is the module ntdll.dll, version: 10.0.19041.1806.
Also had a very stable sim for a long time, the last 2 days or so I have had a CTD on every single flight, unable to complete any. Different parts of the world too, some from Sweden, others in Chicago. Same error message in event viewer too
Faulting module name: ntdll.dll, version: 10.0.22000.832, time stamp: 0x3907dfbc
Exception code: 0xc0000374
I am just trying a flight limiting the FPS to 30, i read something about that, i let you know on landing, or before if another CTD is occurying
and right there, you have captured the issue that individuals on this thread face when offering up potential cures.
By its nature, this issue is a moving target and does not appear to occur at any predictable point in a session. The fact that there has been an apparently sudden increase in CTDs, sometimes without any apparent changes to client software, will probably be useful in finding the issue.
The best chance of finding the solution will be how the devs are hopefully doing, by collecting as much info as possible, via submissions from ALL sufferers.
It looks to me, like an issue with how the client code handles the delays caused by increased traffic on the servers/network, but I’m just guessing. 
Same there. Tons of errors and CTD since yesterday.
Same for me!
I stayed for weeks without any CTD I even thought I was done with it and since yesterday it doesn’t stop 3 crashes without error message.
The first arrived after about 2h30 of flight
The second after 3h30 during the descent to Orly
and the third 30 seconds after takeoff
Fenix A320 without GSX or Mods apart from IVAO and the Orly scene
latest Nvidia driver I have absolutely nothing touched the sim or windows
i agree with you and just try to see if it can be relative to my GPU temperature.
I’ve been having the CTD’s since Friday (UK). Same flight LIRF - EGKK using Fenix. Never had so many CTD’s.
Just done the above flight and the return leg, with no CTD;s and smooth as silk.
To stop my CTD’s, I turned off Live Weather!
Forgot to flag this as an answer to your post:
Do you have any mods installed? If so, which one(s)?
What plane were you flying?
Fenix A320
What were your departure and arrival airports?
Tried multiple routes (LSZH-LGKR, EGPH-LFSB, EGLL-LSZH)
Did you have live weather enabled?
Yes
Did you have live traffic enabled?
No
Are you on SU9 or SU10 beta?
Latest SU10 beta
What is your GPU and what driver version are you using?
RTX 3080Ti, 512.77
Are you using DX11 or DX12?
Tried both, CTD with both
Are you on Windows 10 or 11?
Windows 10