MSFS Application Error - memory could not be read

I saw in my windows event viewer under general that at the same time with the application error was a nvidia display error.
So there where no blackscreen, artifacts or something like that before the memory message appears.

Maybe someone can check if he get this error too?

I did a new installation of the nvidia driver (no beta)

Right now iam in a 5 hour flight with the pmdg737. Iam now 2 hours in the air.

I get this errors mostly after 3 hours airtime or right in the sim menue ideling 30min.