Go in General Options > Accessibility and change cockpit interaction system from Lock to Legacy.
Then go in your control options and make sure Cockpit Interaction - Primary is bound to left mouse button.
if you’d like to try using the new “Lock” mode, where you “lock” on to a specific control that gets highlighted in blue and then interact with it (the idea is to prevent your mouse floating on to the wrong control while you’re trying to adjust something) you also need to bind Cockpit Interaction - Primary (Lock) in controls options.