You have RTX 5080 and probably NVIDIA drivers that are either up to date or the latest version. By default, MSFS 2020 installs with DX11 enabled, not DX12 - that can cause CTDs during loading. I recommend editing usercfg.opt file and changing DX11 to DX12 if you want to use the latest NVIDIA driver.
To do this, you need to edit usercfg.opt file and modify the line
PreferD3D12 0
Change the number 0 to 1
and save the changes.
CTD during loading MSFS 2020 with DX11 selected are a known and confirmed bug.
https://forums.flightsimulator.com/t/msfs-2020-ctd-during-loading-with-or-without-nvidia-app-installed-dx11/732584